Acute Porphyria Drug Database

D07XC03 - Mometasone
Not porphyrinogenic
NP

Rationale
The glucocorticoid is stated in several references not to be porphyrinogenic. Probably only insignificant systemic exposure.
Chemical description
(To be edited, initial data ST OCT 04) Strong glucocorticoid salve, momethasone 0.001%, used in severe plaque psoriasis. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe. .

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