Administered only in 1 mg-dose. Metabolised by CYP 3A4. Considered safe for use in references..

(To be edited, initial data ST OCT 04) Opioid analgesic, chemically related to fentanyl, used (1 mg / dose) for general anesthesia in short and moderately short surgery. Extensively metabolized by CYP3A4 in the liver. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use South African list: use French list: use

Uneventful use reported in 1 patient with acute porphyria.