P02DA01 - Niclosamide |
Propably not porphyrinogenic |
PNP |
Rationale
Probably not significantly absorbed. Observe that grapefruit juice (CYP-inducer!) should be avoided for use as an agent decreasing intestinal mucous secretion in Taenia infections.
Chemical description
(To be edited, initial data ST OCT 04) Vermicide used against Taenia and Diphyllobothrium. Aministered as tablets in a single dose of 2 g (adults) Absorbed only to a very small extent. Inhibitor of CYP 2D6. South African list: No data/avoid
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