Acute Porphyria Drug Database

S02BA07 - Betamethasone
Propably not porphyrinogenic
PNP

Rationale
Probably only restricted absorption. Glucocorticoids: Several references: use/authorised/safe. Isopropanol: Possibly porphyrinogenic in heavy exposure.
Chemical description
(To be edited, initial data ST OCT 04) Strong glucocorticoid administered as ear drops in aqueous isopropanol solution. used in external otitis. South African list: use French list: authorized Kalman, Bonkowski: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias in Bondy PK, RosenbergLE (eds.): Duncan's Disease of metabolism. Philadelphia, WB Saunders,1980, p 939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997 : safe

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