Monograph
C03AA01 - Bendroflumethiazide |
Propably not porphyrinogenic |
PNP |
Rationale
Sulfonamide type of drug. Clinical experience points, however, to non-porphyrinogenicity.
Chemical description
sulfonamide type of drug.
Therapeutic characteristics
Thiazide diuretic and antihypertensive.
Metabolism and pharmacokinetics
More specific data on metabolism are lacking. No observations of CYP interaction. Mainly eliminated via non-renal mechanisms, only 30 % excreted in unchanged form in urine.
Personal communication
Thunell, patient report tolerated (n=1). Andersson, patient report (n=11): tolerated.
IPNet drug reports
Uneventful use reported in 37 patients with acute porphyria.
Similar drugs
Tradenames
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Aprinox · Bendroflumethiazide · Neo-Naclex · Urizide 
Bendroflumethiazide
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