Monograph

C09BA03 - Lisinopril and Diuretics

Not porphyrinogenic

Rationale

The two pharmacologically active substances lisinopril and hydrochlorothiazide, are not metabolised.

Chemical description

Lisinopril: ACE-inhibitor. Exceted in urine in unchanged form. Hydrochlorthiazide: Thiazide diuretic, sulfonamide congener Eliminated in urine in unchanged form. Probably no CYP-affinity. Lisinopril: Andersson, patient report (n=7): tolerated. South African list: use with care. French list: authorized. Hydrochlorthiazide: South African list: use. French list: authorized. Australian list: unsafe associated with attacks. Thunell, patient report (n=1): tolerated. Andersson, patient reports (n=10): tolerated. Martindale: Hydrochlorthiazide has been associated with acute attacks of porphyria and is considred unsafe in porphyric patients. EPI-list: sulfonamides on the unsafe list.

IPNet drug reports

Uneventful use reported in 1 patient with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes C09B / C09BA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Lisinopril / Hydrochloorthiazide · Lisinopril/Hydrochloorthiazide Aurobindo 20/12,5 mg, tabletten · Lisinopril/Hydrochloorthiazide CF 20/12,5 mg, tabletten · Lisinopril/Hydrochloorthiazide Sandoz 20/12,5, tabletten 20/12,5 mg · Lisinopril/Hydrochloorthiazide STADA 10/12,5 mg, tabletten · Lisinopril/Hydrochloorthiazide Viatris 20/12,5 mg, tabletten

Belgium

Co-Lisinopril · Co-Lisinopril EG 20 mg - 12.5 mg comp. · Co-Lisinopril Sandoz 10 mg - 12.5 mg comp. · Co-Lisinopril Sandoz 20 mg - 12.5 mg comp. · Co-Lisinopril Teva 20 mg - 12.5 mg comp. · Co-Lisinopril Viatris 20 mg - 12.5 mg comp. · Zestoretic · Zestoretic 20 mg - 12.5 mg comp.

United Kingdom

Carace 10 Plus · Carace 10 Plus tablets · Carace 20 Plus · Carace 20 Plus tablets · Caralpha · Caralpha 10mg/12.5mg tablets · Caralpha 20mg/12.5mg tablets · Lisicostad · Lisicostad 10mg/12.5mg tablets · Lisicostad 20mg/12.5mg tablets · Lisinopril · Lisinopril 10mg / Hydrochlorothiazide 12.5mg tablets · Lisinopril 20mg / Hydrochlorothiazide 12.5mg tablets · Lisoretic · Lisoretic 10mg/12.5mg tablets · Lisoretic 20mg/12.5mg tablets · Zestoretic 10 · Zestoretic 10 tablets · Zestoretic 20 · Zestoretic 20 tablets

Denmark

Kombinor · Lisinoplus · Lisinopril / Hydrochlorthiazid · Lisinopril/Hydrochlorthiazid "Sandoz" · Lisinopril-hydrochlorthiazid · Lisinopril-hydrochlorthiazid "Actavis"

Norway

Lisinoplus · Lisinopril/Hydroklortiazid Actavis · Lisiplus al · Lisiplus stada · Zestoretic

Poland

Lisiprol HCT · Skopryl Plus · Toralis

Luxembourg

Co-Lisinomyl · Co-Lisinomyl Viatris · CO-LISINOPRIL · CO-LISINOPRIL EG · LISINOPRIL Comp · LISINOPRIL-RATIOPHARM COMP. · Zestoretic

Finland

Lisinopril/Hydrochlorothiazide Orion

Serbia

Iruzid · Iruzid® · Lizopril · Lizopril® H · Skopryl plus · Skopryl plus®

Acute Porphyria Drug Database

Monograph