Monograph
D01AC10 - Bifonazole |
Propably not porphyrinogenic |
PNP |
Rationale
Inhibitor of CYPs 17 (potent), C19 (aromatase), 2E1, 11B1 and 3A4. Probably insignificant systemic exposure.
Chemical description
Imidazole antimycotic for dermatological use (creme 1%). Inhibitor of several CYPs. Systemic absorbtion from the skin is very low; 0.6-0.8 %.
Similar drugs
Tradenames
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