Monograph

D01AE15 - Terbinafine

Propably not porphyrinogenic

Rationale

Terbinafine (ATC code: D01A E15) for topical application is classified as Probably not porphyrinogenic because of minimal systemic exposure. For more details of the metabolism of terbinafine please refer to the monograph of terbinafine for systemic use (ATC code: D01B A02).

Hepatic exposure

Negligible

Metabolism and pharmacokinetics

Less than 5% of the dose is absorbed after topical application and systemic effect is therefore very limited (SPC).

IPNet drug reports

Uneventful use reported in 6 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes D01A / D01AE or go back.

References

#	Citation details	PMID
*	Summary of Product Characteristics
1.	Norwegian medicines agency. Summary of Product Characteristics (SPC). terbinafin.

Citation details

PMID

Summary of Product Characteristics

Norwegian medicines agency. Summary of Product Characteristics (SPC). terbinafin.

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