Monograph

D07AA02 - Hydrocortisone

Propably not porphyrinogenic

Rationale

Probably only insignificant absorption. Ligand to PXR. Substrate for CYPs 3A4, 3A7, 11 B2. Inducer and inhibitor (!) of CYP 3A4. Several references stating non-porphyrinogenicity.

Chemical description

Mild glucocorticoid 0.1 % ointment used in dermatology. Systemic exposure on application on large areas of the body. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncanâ€™s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.

IPNet drug reports

Uneventful use reported in 8 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes D07A / D07AA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Hydrocortison · Hydrocortison crème 10 mg/g FNA Fagron, crème · Hydrocortison Tiofarma 10 mg/g, creme · Hydrocortison zalf 10 mg/g, zalf · Hydrocortison-vaselinecrème · Hydrocortison-vaselinecrème DMB 1% FNA, crème 10 mg/g

Belgium

Cremicort · Cremicort 1 % crème · Hydrocortisone · Conforma Hydrocortisone 10 mg/g crème · Pannocort · Pannocort 1 % crème pot

United Kingdom

Bites Stings · Pinewood Bites and Stings Relief 1% cream · Boots Bite and Sting Relief Hydrocortisone · Boots Bite and Sting Relief Hydrocortisone 1% cream · Derma Hydrocortisone · Boots Derma Care Hydrocortisone 1% ointment · Derma Care Hydrocortisone 1% cream · Dermacort hydrocortisone · Dermacort hydrocortisone 0.1% cream · Dioderm · Dioderm 0.1% cream · Efcortelan · Efcortelan 0.5% cream · Efcortelan 0.5% ointment · Efcortelan 1% cream · Efcortelan 1% ointment · Efcortelan 2.5% cream · Efcortelan 2.5% ointment · Exe-Cort Hydrocortisone · Exe-Cort Hydrocortisone 1% cream · Hc45 Hydrocortisone · Hc45 Hydrocortisone 1% cream · Hydrocortisone · Hydrocortisone 0.5% cream · Hydrocortisone 0.5% ointment · Hydrocortisone 0.5% ointment 50% in White soft paraffin · Hydrocortisone 1% cream · Hydrocortisone 1% cream 50% in Aqueous cream · Hydrocortisone 1% in White soft paraffin · Hydrocortisone 1% lotion · Hydrocortisone 1% ointment · Hydrocortisone 2% in White soft paraffin · Hydrocortisone 2% lotion · Hydrocortisone 2.5% cream · Hydrocortisone 2.5% in White soft paraffin · Hydrocortisone 2.5% ointment · Hydrocortisone Bite and Sting Relief 1% cream · Lanacort · Lanacort 1% cream · Lanacort 1% ointment · Mildison Lipocream · Mildison Lipocream 1% cream · Skincalm Hydrocortisone · Skincalm Hydrocortisone Bite and Sting Relief 1% cream · Zenoxone · Zenoxone 1% cream

Denmark

Hydrokortison · Hydrokortison "Evolan" · Mildison · Mildison Lipid

Norway

Hydrokortison Evolan · Mildison Lipid

Poland

Dermocort · Hydrocort CHEMA · Hydrocortisonum Aflofarm · Hydrocortisonum AFP · Hydrocortisonum Amara · Hydrocortisonum oceanic · Hydrocortisonum Ziaja · Hydrokortyzon Allefin · Hydrokortyzon Allefin Max · Maxicortan

Luxembourg

CORTISEDERMYL · Cremicort · PANNOCORT · SOVENTOL · SOVENTOL-0,5% · Soventol Hydrocortisonacetat

Iceland

Hydrokortison · Hydrokortison Evolan · Mildison · Mildison Lipid

Finland

Hydrocortison · Hydrocortison-ratiopharm · Hydrocortisone · Hydrocortisone Orifarm

Serbia

Hydrocortison · Hydrocortison Galenika

Acute Porphyria Drug Database

Monograph