Monograph
D07AC04 - Fluocinolone Acetonide |
Not porphyrinogenic |
NP |
Rationale
Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
Synthetic fluoroderivative of hydrocrtisone. Strong glucocorticoid, creme/salve 0.025%, used in psoriasis and other glucocorticoid sensitive dermatoses. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
Tradenames and packages
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