Monograph

D10AD03 - Adapalene

Propably not porphyrinogenic

Rationale

No data on metabolism. Probably insignificant systemic exposure in dermal use.

Chemical description

Adapalene gel / creme 0.1% for dermal use in acne vulgaris. Retinoidelike substance with antiinflammatory action. Low percutaneous absorbtion, plasma levels below 0.15 ng/ml.

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Tradenames

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