Monograph
D10AF01 - Clindamycin |
Propably not porphyrinogenic |
PNP |
Rationale
Clindamycin (ATC code: D10A F01) for topical administration is safety classified as Probably not porphyrinogenic because of minimal hepatic exposure.
For more details on the metabolism of clindamycin please refer to the monograph of clindamycin for systemic use (ATC code: J01F F01).
Therapeutic characteristics
Clindamycin topical solution is an antibiotic indicated for the treatment of acne vulgaris.
Hepatic exposure
Insignificant
Metabolism and pharmacokinetics
After topical administration low levels of clindamycin can be found in serum, 0-3 ng/mL, which is well below 1 µM hepatic exposure.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Summary of Product Characteristics | |
| 1. | Norwegian medicines agency. Summary of Product Characteristics (SPC). Dalacin liniment.
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Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Clindamycine 
Zindaclin 
Clinwas · Dalacin · Zindaclin 
Dalacin T · Zindaclin 
Dalacin 
Clindamycine · Dalacin 
Clindacne · Clindalin · Dalacin T · Klindacin T · Normaclin 
Dalacin 
Dalacin 
Clindasome
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