Monograph

D10AX03 - Azelaic Acid

Possibly porphyrinogenic

Rationale

Endogenous organic acid with significant systemic exposure in dermal use

Chemical description

Azelaic acid, endogenous antibacterial substance in creme 200 mg mg / g for dermal use twice daily in acne of moderate severity. Less than 5 % is absorbed through the skin. Urinary excretion is stated to be 25 mg/24 h.

IPNet drug reports

Uneventful use reported in 1 patient with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes D10A / D10AX or go back.

Tradenames

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