Monograph
G04CB01 - Finasteride |
Possibly porphyrinogenic |
PSP |
Rationale
Substrate for CYP 3A4. Conflicting evidence of porphyrinogenicity.
Chemical description
4-azasteroide used in prostatic hypertrophy, 5 mg/d Competetive inhibitor of 5-alpha reductase which converts testosterone to the more potent androgen dihydroform needed for the growth of the prostatic tissue. Metabolized by 3A4. South African list: use with extreme caution only. French list: authorized
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
Tradenames
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