Monograph

H02AB01 - Betamethasone

Propably not porphyrinogenic

Rationale

Glucocorticoid. Several references consider it safe.

Chemical description

Glucocorticoid used in treatment of staus asthmaticus, severe allergic conditions, anaphylaxis, etc. Mineralocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moores list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncans Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939: safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe

Therapeutic characteristics

Hepatic exposure

Metabolism and pharmacokinetics

Preclinical data

Personal communication

Published experience

IPNet drug reports

Uneventful use reported in 7 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes H02A / H02AB or go back.

Tradenames

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