Monograph

H02AB01 - Betamethasone

Propably not porphyrinogenic

Rationale

Glucocorticoid. Several references consider it safe.

Chemical description

Glucocorticoid used in treatment of staus asthmaticus, severe allergic conditions, anaphylaxis, etc. Mineralocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moores list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncans Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939: safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe

Therapeutic characteristics

Hepatic exposure

Metabolism and pharmacokinetics

Preclinical data

Personal communication

Published experience

IPNet drug reports

Uneventful use reported in 7 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes H02A / H02AB or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Celestone · Celestone Chronodose, suspensie voor injectie 5,7 mg/ml

Belgium

Celestone · Celestone 0.5 mg/ml gtts buv. sol. · Celestone 4 mg/ml sol. inj. i.lés./i.v./i.artic./i.burs./i.m. amp. · Celestone Chronodose 3 mg/ml - 4 mg/ml susp. inj. p.artic./i.lés./i.artic./i.derm./i.burs./i.m. flac. · Diprophos · Diprophos 10 mg/2 ml - 4 mg/2 ml susp. inj. p.artic./i.lés./i.artic./i.derm./i.m. amp. · Diprophos 5 mg/ml - 2 mg/ml susp. inj. p.artic./i.lés./i.artic./i.derm./i.m. amp. · Diprophos Disposable Syringe 5 mg/ml - 2 mg/ml susp. inj. p.artic./i.lés./i.artic./i.burs./i.m. ser. préremplie

United Kingdom

Betamethasone · Betamethasone 4mg/1ml solution for injection ampoules · Betamethasone 500microgram soluble tablets sugar free · Betnelan · Betnelan 500microgram tablets · Betnesol · Betnesol 4mg/1ml solution for injection ampoules · Betnesol 500microgram soluble tablets

Denmark