Monograph
H02AB04 - Methylprednisolone |
Possibly porphyrinogenic |
PSP |
Rationale
Glucocorticoid. Substrate, inhibitor and activator / stimulator of CYP 3A4. Several references consider it safe.
Chemical description
Glucocorticoid for intramuscular administration or local injection. Metabolized by CYP 3A4. Glucocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moore's list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939. :safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe
Similar drugs
Tradenames
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Depo-Medrol · Methylprednisolon · Solu-Medrol 
Depo-Medrol · Depo-Medrol + Lidocaine · Medrol · Medrol A · Medrol Pak · Methylprednisolon · Solu-Medrol · Solu-Medrol S.A.B. · Solu-Medrol S.A.B. Act-O-Vial 
Metilprednisolona · Solu-Moderin · Urbason 
Depomedrol · Medrol · Metildrol · Metilprednisolone · Solumedrol · Urbason 
Lemod Solu · Medrol · Medrol a · Metilprednisolon · Solu - Medrol act-o-Vial 
Depo-Medrone · Medrone · Methylprednisolone · Methylprednisolone sodium succinate · Solu-Medrone 
Depo-Medrol · Medrol · Methylprednisolone · Solu-medrol 
Depo-Medrol · Medrol · Methylprednisolone · Metylprednisolon · Solu-Medrol 
Depo-Medrol · Depo-Medrol Lidokaina · Medrol · Meprelon · Methylprednisolone · Metypred · Solu-Medrol 
Depo Medrol · Depo Medrol + Lidocaine · Medrol · Medrol pak · Medrol-a · Methylprednisolone · Solu-Medrol · Solu-Medrol s.a.b. · Solu-Medrol S.A.B. Act-O-Vial 
Depo-Medrol · Solu-Medrol 
Depo-Medrol · Medrol · Metypred · Solomet · Solu-Medrol 
Depo-Medrol · Medrol · Solu-Medrol 
Lemod
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