Monograph

H02AB07 - Prednisone

Possibly porphyrinogenic

Rationale

Glucocorticoid. Inducer of CYP 3A4. Several references stating non-porphyrinogenicity.

Chemical description

Used in systemic glucocorticoid treatment. Glucocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moore's list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncanâ€™s Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939. :safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe

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