Monograph

A04AA03 - Tropisetron

Propably not porphyrinogenic

Rationale

Metabolised by CYP 2D6. Substrate for CYPs 2C9 and 3A4. No clinical observations of CYP-induction.

Chemical description

Serotonine receptor antagonist used as antiemetic under chemotherapy, or as prophylaxis or treatment of postoperative nausea; 5-15 mg/d perorally or parenterally. Metabolized mainly by hydroxylation by the polymorphic CYP 2D6. Weak inhibitor of CYP 2D6. No clinical data pointing to CYP-inducing properties. South African list: No data/avoid

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Tradenames

This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.

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Show more details and information about the listed tradenames

Novaban

Tropisetron

Navoban

Acute Porphyria Drug Database

Monograph