Monograph

J01DD02 - Ceftazidime

Propably not porphyrinogenic

Rationale

Not metabolised. No data pointing to CYP interaction. Conflicting references. Some clinical experience of non-porphyrinogenicity.

Chemical description

Parenterally administered (up to 1 gx 2) betalactamase stable cephalosporin antibiotic used e.g in nosocomial pulmonary infections, respiratory tract infections in cystic fibrosis, urinary tract infections and acute meningitis. Not metabolized, excreted in unchanged form by the kidneys. No data pointing to CYP-interaction. South African list: use with caution. French list: use. Andersson: Occasionally used without any side effects.

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