Monograph
J01MA06 - Norfloxacin |
Propably not porphyrinogenic |
PNP |
Rationale
CYP 3A4-inhibitor. Conflicting references but some clinical experience of non-porphyrinogenicity.
Chemical description
Quinolone antibiotic. Some metabolism takes place and several metabolites have been identified in urine. About 30% is excreted in urine in unchanged form within 24 hours, while the same amount is recoverd in faeces. Inhibitor of CYP 3A4. Some interference with fluorimetric determination of urinary porphyrins, reported. Australian list: safe. South African list: use with extreme caution only. French list: use. S Thunell, patient inquiry: well tolerated(n=4). Andersson:
IPNet drug reports
Uneventful use reported in 18 patients with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
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Norfloxacine 
Norfloxacine 
Norfloxacino 
Norfloxacina 
Nolicin · Norfloxacin · Norfloxacina 
Norfloxacin · Utinor 
Nolicin 
Norfloxacine 
Nolicin · Norflox 
Nolicin · Uricin
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