Monograph
J01XX01 - Fosfomycin |
Propably not porphyrinogenic |
PNP |
Rationale
Phosphonic acid derivative, not metabolised. Probably devoid of CYP affinity.
Chemical description
Phosphonic acid derivative broad spectrum antibiotic used in urinary tract infections. Most of the dose is eliminated unchanged in urine. No data pointing to CYP interaction. South African list: no data/avoid. French list: use.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
Tradenames
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