Monograph

J02AA01 - Amphotericin B

Propably not porphyrinogenic

Rationale

Probably not significantly metabolised. Three references state non-porphyrinogenicity.

Chemical description

Antimycotic substance for systemic use in candidemia and other severe generalized fungal infections. Obtained from from Streptomyces nodosus. Stored in the body for long periods, being slowly excreted in unchanged form in urine. Amphotericin B has been shown to decrease hepatic CYP content and function in rat studies. In contrast liposomal preparations of the substance do not give rise to this effect. EPI-list: safe. South African list: use with caution. French list: use.

IPNet drug reports

Uneventful use reported in 1 patient with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes J02A / J02AA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Abelcet · Abelcet 5 mg/ml lipide complex, concentraat voor suspensie voor infusie · AmBisome liposomale amfotericine B · AmBisome liposomale amfotericine B 50 mg, poeder voor dispersie voor infusie · Fungizone ad Perfusionem · Fungizone ad Perfusionem, poeder voor infusievloeistof 50 mg

Belgium

Abelcet Complex · Abelcet Lipid Complex 5 mg/ml disp. perf. (à diluer) i.v. flac. · AmBisome Liposomale · AmBisome Liposomale 50 mg disp. perf. (pdr.) i.v. flac.

United Kingdom

Abelcet · Abelcet 100mg/20ml concentrate for dispersion for infusion vials · Abelcet 50mg/10ml concentrate for suspension for infusion vials · Abelcet 50mg/10ml suspension for injection vials · AmBisome · AmBisome 50mg powder for solution for infusion vials · AmBisome 50mg powder for solution for injection vials · AmBisome Liposomal · AmBisome Liposomal 50mg powder for dispersion for infusion vials · Amphocil · Amphocil 100mg powder for solution for infusion vials · Amphocil 50mg powder for solution for infusion vials · Amphocil 50mg powder for solution for injection vials · Amphotericin B · Amphotericin B liposomal 50mg powder for dispersion for infusion vials · Fungizone · Fungizone 50mg powder for concentrate for solution for infusion vials

Denmark