Monograph

J07BC01 - Hepatitis B, Purified Antigen

Propably not porphyrinogenic

Rationale

Based on the pharmacokinetics of the hepatitis B, purified antigen vaccine, there are no conceivable porphyrinogenic effects.

Chemical description

Hepatitis B surface antigen

Therapeutic characteristics

The vaccine is indicated for the active immunization of adults, children and infants against hepatitis B. It is administered by intramuscular injections according to a three or four dose schedule.

Metabolism and pharmacokinetics

The hepatitis vaccine is not metabolized by the cytochrome P450 system.

IPNet drug reports

Uneventful use reported in 1 patient with acute porphyria.

References

#	Citation details	PMID
*	Government bodies
1.	Norwegian Institute of Public Health. Vaksinasjonsveilederen. www.fhi.no (updated 13.10.2015).
*	Summary of Product Characteristics
2.	The electronic Medicines Compendium (emc). Summary of Product Characteristics (SPC). HBVAXPRO. (Last edition: March 2014).

Citation details

PMID

Government bodies

Norwegian Institute of Public Health. Vaksinasjonsveilederen. www.fhi.no (updated 13.10.2015).

Summary of Product Characteristics

The electronic Medicines Compendium (emc). Summary of Product Characteristics (SPC). HBVAXPRO. (Last edition: March 2014).

Similar drugs

Explore alternative drugs in similar therapeutic classes J07B / J07BC or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Engerix-B · Engerix-B 20 microgram/1 ml, suspensie voor injectie · Engerix-B 20 microgram/1 ml, suspensie voor injectie in een voorgevulde spuit · Engerix-B 20 microgram/1ml, suspensie voor injectie · Engerix-B Junior 10 microgram/0,5 ml, suspensie voor injectie · Fendrix · Fendrix, suspensie voor injectie · HBVAXPRO · HBVAXPRO 10 microgram/ml, suspensie voor injectie in flacon · HBVAXPRO 10 microgram/ml, suspensie voor injectie in voorgevulde spuit · HBVAXPRO 40 microgram/ml, suspensie voor injectie in flacon · HBVAXPRO 5 microgram/0,5 ml, suspensie voor injectie in flacon · HBVAXPRO 5 microgram/0,5 ml, suspensie voor injectie in voorgevulde spuit · HEPLISAV B · HEPLISAV B 20 uq/dosis, oplossing voor injectie n voorgevulde spuit · PreHevbri · PreHevbri 10 microgram, suspensie voor injectie

Belgium

Engerix B · Engerix B 20 µg/1 ml susp. inj. s.c./i.m. flac. · Engerix B 20 µg/1 ml susp. inj. s.c./i.m. ser. préremplie · Engerix B Junior 10 µg/0.5 ml susp. inj. s.c./i.m. flac. · Engerix B Junior 10 µg/0.5 ml susp. inj. s.c./i.m. ser. préremplie · Fendrix · Fendrix susp. inj. i.m. ser. préremplie · HBVaxPro · HBVaxPro 10 µg/ml susp. inj. s.c./i.m. flac. · HBVaxPro 10 µg/ml susp. inj. s.c./i.m. ser. préremplie · HBVaxPro 40 µg/ml susp. inj. s.c./i.m. flac. · HBVaxPro 5 µg/0.5 ml susp. inj. s.c./i.m. flac. · HBVaxPro 5 µg/0.5 ml susp. inj. s.c./i.m. ser. préremplie · Heplisav B · Heplisav B 20 µg sol. inj. i.m. ser. préremplie

United Kingdom

Engerix B · Engerix B 10micrograms/0.5ml vaccine suspension for injection pre-filled syringes · Engerix B 10micrograms/0.5ml vaccine suspension for injection vials · Engerix B 20micrograms/1ml vaccine suspension for injection pre-filled syringes · Engerix B 20micrograms/1ml vaccine suspension for injection vials · Fendrix · Fendrix 20micrograms/0.5ml vaccine suspension for injection pre-filled syringes · HBVAXPRO · HBVAXPRO 10micrograms/1ml vaccine suspension for injection pre-filled syringes · HBvaxPRO 10micrograms/1ml vaccine suspension for injection vials · HBvaxPRO 40micrograms/1ml vaccine suspension for injection vials · HBVAXPRO 5micrograms/0.5ml vaccine suspension for injection pre-filled syringes · HBvaxPRO 5micrograms/0.5ml vaccine suspension for injection vials · PreHevbri · PreHevbri 10micrograms/1ml suspension for injection vials

Denmark