Monograph
M02AA13 - Ibuprofen |
Not porphyrinogenic |
NP |
Rationale
Probably insignificant systemic exposure.
Chemical description
Gel 5%. Analgetic and antiinflammatory gel for dermal application effective through its cyclooxygenas inhibiting effect. Hydroxylated by CYP2C9 (major enzyme) and 2C8. Inhibitor of CYP 2C9. Excreted as two metabolites. No data pointing to CYP-induction No data on systemic exposure but is considerd low. South African list: use.
French list: avoid.
IPNet drug reports
Uneventful use reported in 4 patients with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Nurofen 
Extrapan Ibuprofenum · Ibuprofen gel · Nurofen 
Aragel · Articalm · Azodermol · Diltix · Gelib · Ibucalm · Ibudol · Ibudol Roll-on · Ibufen · Ibukey · Ibustick · Novidol · Rolibfar 
Biofen · Dolgit · Ibuprofen · Ibutop · Larofen · Nurofen · Nurofen gel · Salipren 
Boots Ibuprofen · Boots Ibuprofen Max Strength · Cuprofen · Fenbid · Fenbid Forte · Ibucalm Ibuprofen · Ibuderm · Ibugel · Ibugel Forte · Ibuleve · Ibuleve Maximum Strength · Ibuleve Speed · Ibuleve Sports · Ibumousse · Ibuprofen · Ibuprofen gel · Ibuspray · Ibutop Ralgex Ibuprofen · Lloydspharmacy Maximum Strength Ibuprofen · Mentholatum Ibuprofen · Nurofen gel · Nurofen plaster · Phorpain · Phorpain Maximum Strength · Proflex · Proflex Pain Relief · Radian B Ibuprofen 
Ibutop 
Ibux 
Dip Rilif · Dolgit · Ibum · Ibument · Ibuprofen · Ibuprom · Ibured · Ibured Forte · Metafen Forte · Nurofen 
Dolgit · Extrapan Ibuprofenum · Nurofen · proff 
Buranagel 
Deep · Ibuprofens · Ibutop · Nurofen 
Deep · Ibutop
© NAPOS 2025