Monograph

M02AA13 - Ibuprofen

Not porphyrinogenic

Rationale

Probably insignificant systemic exposure.

Chemical description

Gel 5%. Analgetic and antiinflammatory gel for dermal application effective through its cyclooxygenas inhibiting effect. Hydroxylated by CYP2C9 (major enzyme) and 2C8. Inhibitor of CYP 2C9. Excreted as two metabolites. No data pointing to CYP-induction No data on systemic exposure but is considerd low. South African list: use. French list: avoid.

IPNet drug reports

Uneventful use reported in 4 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes M02A / M02AA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Nurofen · Nurofen pleister 200 mg

Belgium

Extrapan Ibuprofenum · Extrapan Ibuprofenum Gel 5 % gel · Ibuprofen gel · Ibuprofen Teva 5 % gel · Nurofen · Nurofen Patch 200 mg patch cut. sachet

United Kingdom

Boots Ibuprofen · Boots Ibuprofen 5% gel · Boots Ibuprofen Max Strength · Boots Ibuprofen Max Strength 10% gel · Cuprofen · Cuprofen 5% gel · Fenbid · Fenbid 5% gel · Fenbid Forte · Fenbid Forte 10% gel · Ibucalm Ibuprofen · Ibucalm Ibuprofen Pain Relief 5% gel · Ibuderm · Ibuderm 5% gel · Ibugel · Ibugel 5% gel · Ibugel Forte · Ibugel Forte 10% gel · Ibuleve · Ibuleve 5% gel · Ibuleve 5% Mousse · Ibuleve 5% spray · Ibuleve Max Strength Pain Relief 10% Gel · Ibuleve Pain Relief 5% Gel · Ibuleve Pain Relief 5% Spray · Ibuleve Maximum Strength · Ibuleve Maximum Strength 10% gel · Ibuleve Speed · Ibuleve Speed Relief 5% gel · Ibuleve Speed Relief 5% spray · Ibuleve Speed Relief Max Strength 10% gel · Ibuleve Sports · Ibuleve Sports 5% gel · Ibumousse · Ibumousse 5% · Ibuprofen · Ibuprofen 5% spray · Numark Ibuprofen Pain Relief 5% gel · Ibuprofen gel · Ibuprofen 10% gel · Ibuprofen 5% gel · Ibuprofen Pain Relief Maximum Strength 10% gel · Ibuspray · Ibuspray 5% spray · Ibutop Ralgex Ibuprofen · Ibutop Ralgex Ibuprofen 5% gel · Lloydspharmacy Maximum Strength Ibuprofen · Lloydspharmacy Maximum Strength Ibuprofen 10% gel · Mentholatum Ibuprofen · Mentholatum Ibuprofen 5% gel · Nurofen gel · Nurofen 5% gel · Nurofen Maximum Strength 10% gel · Nurofen plaster · Nurofen Joint & Back Pain Relief 5% gel · Nurofen Joint & Back Pain Relief Max Strength 10% gel · Nurofen Joint & Muscular Pain Relief 200mg medicated plasters · Phorpain · Phorpain 5% gel · Phorpain Maximum Strength · Phorpain Maximum Strength 10% gel · Proflex · Proflex 5% cream · Proflex Pain Relief · Proflex Pain Relief 5% cream · Radian B Ibuprofen · Radian B Ibuprofen 5% gel · Radian B Ibuprofen Massage stick

Denmark

Ibutop

Norway

Ibux

Poland

Dip Rilif · Dolgit · Dolgit Gel · Ibum Sport · Ibument · Ibuprofen Alkaloid-INT · Ibuprofen APTEO MED · Ibuprofen Dr. Max · Ibuprofen HWI pharma services GmbH · Ibuprom Effect zel · Ibuprom Sport spray · Ibured · Ibured Forte · Metafen zel Forte · Nurofen Miesnie i Stawy

Luxembourg

Dolgit · Dolgit Schmerzgel · EXTRAPAN IBUPROFENUM · EXTRAPAN IBUPROFENUM GEL 5% · Nurofen · Nurofen Patch · proff · proff Schmerzcreme

Finland

Buranagel

Latvia

Deep · Deep Relief · Ibuprofens · Ibuprofens LMP · Ibutop · Nurofen

Serbia

Deep · Deep Relief · Ibutop · Ibutop® Cream · Ibutop® Gel

Acute Porphyria Drug Database

Monograph