Monograph
N01AH02 - Alfentanil |
Propably not porphyrinogenic |
PNP |
Rationale
Administered only in 1 mg-dose. Metabolised by CYP 3A4. Considered safe for use in references..
Chemical description
Opioid analgesic, chemically related to fentanyl, used (1 mg / dose) for general anesthesia in short and moderately short surgery. Extensively metabolized by CYP3A4 in the liver. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use South African list: use French list: use
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
Tradenames
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