Acute Porphyria Drugs

Monograph

N02AA01 - Morphine
Not porphyrinogenic
NP

Rationale
Several references as well as significant clinical experience indicate non-porphyrinogenicity.
Chemical description
Opioid analgesic often used in acute porphyric crisis. After conjugation with glucuronic acid to morphine-3-glucuronide it is eliminated by the kidneys. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use EPI-list: safe South African list: use French list: use Kalman, Bonkovsky: safe Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction.Biochem Biophys Acta 543:313, 1978: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: probably safe.
IPNet drug reports
Uneventful use reported in 41 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes N02A / N02AA or go back.
Tradenames
This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.


Diacetylmorfine · Molnex · Morfine · Morfinesulfaat · MS Contin · Oramorph · Sendolor Morphine · MS Contin · MS Direct · Oramorph Dolq · Maracex · Morfina · MST Continus · Oramorph · Sevredol Morphine · Morphinum · MST Continus · Sevredol Morfina · MS Contin · Oramorph · Twice Morfina · Sevredol · Vendal Kapanol · M-retard · Morphin · Morphine · Morphini · MST Continus · Oramorph · Sevre-Long · Sevredol Actimorph · Depodur · Filnarine SR · Morcap SR · Morphgesic SR · Morphine · Morphine 0.1% in Intrasite gel · Morphine 0.2% in Intrasite gel · Morphine hydrochloride · Morphine sulfate · MST Continus · mxl · Oramorph · Sendolor · Sevredol · Zomorph Contalgin · Depolan · Doltard · Malfin · Morfin · Morfinsulfat · Morphinsulfat · Oramorph · Sendolor Contalgin · Dolcontin · Malfin · Morfin · Morfine · Oramorph · Sevre-Long Doltard · Maracex · Morfina · Morphine · Morphini sulfas · MST Continus · Oramorph · Sevredol · Vendal Morphine · MS Contin · MS Direct · Oramorph · Sendolor Contalgin · Morfin · Morphine Molnex · Morphin · Oramorph · Sendolor Doltard · Maracex · Morphin · Morphine · Morphini sulfas · Vendal Morfina · Morphin · Vendal Doltard · Maracex · Morfin · MST Continus · mxl · Sevredol · Vendal Morfin · Oramorph Analgeticna morfinom · Doltard · Kapanol · M-eslon · Morfin · Morfinijev · Morphin · Morphini Sulfas · msi Mundipharma · MST Continus · Opijeva · Oramorph · Sevredol · Substitol
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