Monograph
N02BA51 - Acetylsalicylic Acid, Combinations Excl. Psycholeptics |
Not porphyrinogenic |
NP |
Rationale
Acetylsalicylic acid: Insignificant CYP 2C9 metabolism. Repeatedly experienced to be safe in acute porphyria. Several references consider it safe. Caffeine: Widely used as beverage, no observations of porphyrinogenic side effects.
Chemical description
Acetylsalicylic acid: Water soluble light analgesic, inhibitor of prostaglandin synthesis. Metabolized by conjugation with glycine. Acetylsalicylic acid: MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use EPI-list: safe South African list: use French list: use Kalman, Bonkovsky: safe Merck Index: safe Eales L: Porphyria and the dangerous life-threatening drugs. S Afr Med J 56:914,1979: safe. Thunell; patient inquiry: tolerated n=20)
IPNet drug reports
Uneventful use reported in 22 patients with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
. · Aspirine-C · Excedrin 
Aspirine Cafeine · Aspirine-C · Excedryn & Maux · Perdolan Compositum · Troc Comp 
Actron Compuesto · Acyflox · Aspirina c · Aspirina c Efervescentes · Aspirina Plus · Cafiaspirina · Calmante Vitaminado Perezgimenez · Couldina Acido Acetilsalicilico · Couldina Acido Acetilsalicilico Efervescentes · Excedite · Okaldol Cafeina · Okaldol Dispersables · Sedergine c Efervescentes 
Algopirin · Antinevralgic p · Aspaco · Aspirin Plus c · Aspirin Plus c Forte · Fascomit · Fasconal · Nevralgio 
Alka-Seltzer · Alka-Seltzer XS · Anadin Extra · Anadin Original · Aspav · Aspirin · Aspirin Codeine · Beechams Powders · Co-codaprin · Extra Power Pain Reliever · MigraMax · Original Phensic Aspirin · Paramed 
Treo · Triplo 
. · AntyGrypin · Ascalcin Plus · Aspirin C · Aspirin C Forte · Coffepirine · Dampiryna · Etopiryna · Etopiryna Kontrol · Excedrin MigraStop · FluControl Symptom · Gripex · Kopiryna · Migromin · Polopiryna C · Polopiryna C Plus · Ultrapiryna C · Ultrapiryna Plus · Upsarin C 
Asperine Cafeine · Aspirine c · ass + c 
Treo · Triplo 
Finrexin · Ring · Treo 
Aspirin C · Citramon P · Citramons forte · Upsarin C 
Aspirin
© NAPOS 2025