Monograph
N05AH03 - Olanzapine |
Propably not porphyrinogenic |
PNP |
Rationale
Compare the neuroleptic benzodiazepine clozapine :
Chemical description
Benzodiazepine derivative used in schizophrenia. Metabolized via CYP 1A2 and 2D6. No indications of CYP-inducing effects. Thunell; clinical experience from prolonged treatment (n=1):no porphyric side effects See Holoryd S et al. Psychotropic drugs in acute…(one case) (PMID: 10511069).
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
Tradenames
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