Monograph
A07EA06 - Budesonide |
Propably not porphyrinogenic |
PNP |
Rationale
Substrate for CYPs 3A4. Inhibitor of CYP 2C3.Inducer of CYP 3A5. Several references consider it safe.
Chemical description
Glucocorticoid for local treatment of Mb Crohn. Biovailability 3-50%. Metabolized by CYPs 3A4. South African list: use. French list: authorized. Merck Index: safe Kahlman, Bonkowky: believed to be safe.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
Tradenames
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