Monograph
A07EC02 - Mesalazine |
Propably not porphyrinogenic |
PNP |
Rationale
Relatively low systemic exposure of substance with probably non-CYP metabolism. Acetyl salicylic acid is an inducer of CYP 2C19. Two references state non-porphyrinogenicity.
Chemical description
5-aminosalicylic acid (5-ASA). Antiinflammatory agent in suppositorium or foam for local rectal use, 1 g/d. Low systemic exposure, only about 20 % of the given dose recovered in urine after acetylation in the intestinal mucosa and the liver. South African list: use. EPI-list: use
IPNet drug reports
Uneventful use reported in 6 patients with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
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Asacol · Azzavix · Colitofalk · Kiudro · Mesalazine · Mesavancol · Mezavant · Pentasa · Pentasa Compact · Salofalk · Yaldigo 
Asamovon · Claversal · Colitofalk · Mesalazine · Pentasa 
Asacol · Azzavix · Blenix · Claversal · Claversal Espuma · Mecolvix · Mezavant · Pentasa · Salofalk 
Argonal · Asacol · Asalex · Asamax · Asavixin · Claversal · Lextrasa · Mesaflor · Mesalazina · Mesavancol · Pentacol · Pentasa · Proctasacol 
Mesalazina · Pentasa · Salofalk 
Asacol · Ipocol · Mesalazine · Mesren MR · Mezavant · Octasa · Pentasa · Pentasa Mesalazine · Salcrozine · Salofalk · Zintasa 
Asacol · Mesalazin · Mesavancol · Mezavant · Pentasa · Quintasa · Salofalk 
Asacol · Mesalazin · Mezavant · Pentasa · Salofalk 
Asamax · Crohnax · Mezavant · Pentasa · Salaza · Salofalk 
Claversal · Colitofalk · Mezavant · Pentasa · Salofalk 
Asacol · Pentasa 
Asacol · Mesalazin · Pentasa · Salofalk 
Asacol · Pentasa · Salofalk · Yaldigo 
5-asa · Asacol · Pentasa · Salofalk
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