Monograph
P01BA02 - Hydroxychloroquine |
Possibly porphyrinogenic |
PSP |
Rationale
Partly CYP-metabolised. Compare the 8-aminoquioline primaquine: Inducer of CYPs 1A1, 1A2 and 1B1.
Chemical description
Aminokinoline derivative used in sensitive malaria strains. Administered as tablets in a three-day cure starting with 1200 mg the first day. Vast tissue distribution with accumulation in blood cells and in liver, lungs, kidneys and eyes. Partly converted by CYP 2D6 to de- ethylated metabolites. Slowly excreted with a terminal half life of 50 days. About 25% excreted by the kidneys in unchanged form.
Similar drugs
Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia).
Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway).
What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names
are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Netherlands
Belgium
United Kingdom
Denmark
Norway
Poland
Luxembourg
Iceland
Finland
Latvia
Serbia
