Monograph
R01AC02 - Levocabastine |
Propably not porphyrinogenic |
PNP |
Rationale
Low dose, only insignificant systemic and metabolic exposure.
Chemical description
Selective HI-antagonist used in local treatment of allergic rhinitis. Nasal spray, each dose containing 50 µg levocabastine. Recommended dose gives plasma concentrations in the range 2-9 µg/mL. Excreted in unchanged form (70%) and as glucuronide.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
Tradenames
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