Monograph

R01AD09 - Mometasone

Not porphyrinogenic

Rationale

Insignificant systemic exposure . Several references stating non-porphyrinogenicity of glucocorticoids.

Chemical description

Glucocorticoide nasal spray with very low bioavailability (<0,1 %). EPI-list: safe French list: authorized South African list: use Kalman, Bonkowski: safe The Merck Manual: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias, in Bondy PK, Rosenberg LE (eds.): Duncan's Diseases of Metabolism. Philadelphia, WB Saunders, 1980, p939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: safe

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Tradenames

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