Monograph

R03BB04 - Tiotropium Bromide

Propably not porphyrinogenic

Rationale

Probably insignificant metabolic exposure

Chemical description

Anticholinergic bronchodilator used in inhalation powder (18 ug/dose) in KOL. 75 % excreted in unchanged form in urine, the rest metabolized by CYPs.

IPNet drug reports

Uneventful use reported in 3 patients with acute porphyria.

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Tradenames

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