Monograph
R03CC02 - Salbutamol |
Not porphyrinogenic |
NP |
Rationale
Rather low dose, in large parts excreted unmetabolized. No data pointing to CYP-interaction. Three references consider it safe. Occasional clinical observations of tolerance.
Chemical description
Adrenergic bronchodilator for systemic treatment (tabl. 2 - 4 mg, oral solution 0,4 mg/mL) of asthma, bronchitis and emphysema. Metabolized in the liver. About 35 % excreted in urine in unchanged form. Weak inhibitor of CYP 3A4. EPI-list: safe South African list: use French list: autorized Kauppinen and Mustajoki. Prognosis of acute porphyria... Medicine 1992; 71: 1-13: Reported to be tolerated (n=2) Used in porphyria ward (Sweden).
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
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Ventolin 
Ventolin 
Aldobronquial · Ventolin 
Salbutamol · Ventolin 
Salapin · Salbutamol · Ventmax SR · Ventolin · Volmax 
Ventoline 
Ventilan · Ventolin · Ventoline 
Salbutamol 
Ventolin 
Ventoline 
Ventolin 
Spalmotil
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