Acute Porphyria Drug Database

Monograph

R06AD03 - Thiethylperazine
Propably not porphyrinogenic
PNP

Rationale
Phenotiazines in general are considered safe in several references.
Chemical description
Antiemetic phenotiazine with sedative effect, also used (supp 20 mg/d) in vertigo. Only 3% of the dose is excreted in unmetabolized form. Kalman, Bonkowski: safe (phenotiazines) Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction. Biochem Biophys Acta 543:313, 1978: safe (phenotiazines) Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: safe (phenotiazines)
Similar drugs
Explore alternative drugs in similar therapeutic classes R06A / R06AD or go back.
Tradenames
This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.


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