Monograph
S01EB09 - Acetylcholine |
Not porphyrinogenic |
NP |
Rationale
Acetylcholine is administered locally in the eye and does not enter systemic circulation due to rapid local destruction.
Chemical description
Quaternary ammonium salt
Therapeutic characteristics
A freshly-prepared 1 % aqueous solution of acetylcholine is administered intraocular to obtain a rapid and complete miosis (constriction of the pupil) in various intraocular surgeries.
Hepatic exposure
Hepatic exposure is insignificant.
Metabolism and pharmacokinetics
Rapid local destruction of acetycholine takes place via the action of acetylcholinesterase giving rise to choline and acetic acid.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Summary of Product Characteristics | |
| 1. | The electronic Medicines Compendium (emc). Summary of Product Characteristics (SPC). Miochol.
|
|
| * | Other sources | |
| 2. | Swedish National Formulary. FASS. Miochol-E. www.fass.se (product leaflet)
|
|
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Acetilcolina 
Miochol-E · Miphtel 
Acetilcolina cusi · Miochol-E · Miovisin 
Miochol-e 
Miochol-E
© NAPOS 2025