Grass pollen extracts consists mainly of polypeptides and proteins that are not subject to liver metabolism or interaction with CYP enzymes.

Allergen extract, grass pollen. Contains polypeptides and proteins.

Allergen extracts containing grass pollen are used in allergy immunotherapy, to desensitize people that have an allergy to grass pollen. It is administered as a sublingual tablet or as a subcutaneous injection. It may be used continuously throughout the season or for up to 3to 5 years for long term efficacy (SPC, Senna 2011).

The grass pollen extract consist mainly of polypeptides and proteins, which are expected to be broken down to amino acids and small polypeptides in the lumen of the gastrointestinal tract and in tissues. It is not expected that the allergens is absorbed into the vascular system to any significant extent. No pharmacokinetic studies in animals or clinical studies have been conducted (EMEA, SPC).