Monograph
V03AF05 - Amifostine |
Not porphyrinogenic |
NP |
Rationale
Non-CYP metabolism.
Chemical description
Organic thiophosphate used as a cytoprotective during treatment with cyclophosphamide combined with cisplatine in advanced ovarial cancer. Prodrug, rapidly metabolized by alcaline phosphatase to free phosphatase and the active free thiol.
Similar drugs
Tradenames
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