Monograph

V08CA09 - Gadobutrol

Not porphyrinogenic

Rationale

Gadobutrol is not metabolised. It is excreted unchanged through the kidneys.

Chemical description

Gadobutrol is a nonionic gadolinium chelate.

Therapeutic characteristics

Gadobutrol is used as a magnetic resonance contrast medium. It is administered intravenously.

Hepatic exposure

Not significant.

Metabolism and pharmacokinetics

Gadobutrol is not metabolised and more than 90% of a dose is excreted in the urine within 12 hours.

References

#	Citation details	PMID
*	Drug reference publications
1.	Sweetman SC, editor. Martindale: The complete drug reference. Gadobutrol. Pharmaceutical Press 2009.
*	Summary of Product Characteristics
2.	Norwegian medicines agency. Summary of Product Characteristics (SPC). Gadovist.

Citation details

PMID

Drug reference publications

Sweetman SC, editor. Martindale: The complete drug reference. Gadobutrol. Pharmaceutical Press 2009.

Summary of Product Characteristics

Norwegian medicines agency. Summary of Product Characteristics (SPC). Gadovist.

Similar drugs

Explore alternative drugs in similar therapeutic classes V08C / V08CA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Gadovist · Gadovist 1,0 mmol/ml oplossing voor injectie in voorgevulde spuit/patroon · Gadovist 1,0 mmol/ml, oplossing voor injectie

Belgium

Gadovist · Gadovist 1 mmol/ml sol. inj. i.v. · Gadovist 1 mmol/ml sol. inj. i.v. cart. · Gadovist 1 mmol/ml sol. inj. i.v. cart. flac. · Gadovist 1 mmol/ml sol. inj. i.v. flac. · Gadovist 1 mmol/ml sol. inj. i.v. ser. préremplie

United Kingdom

Gadobutrol · Gadobutrol 1mmol/ml solution for injection 10ml pre-filled syringes · Gadobutrol 1mmol/ml solution for injection 15ml pre-filled syringes · Gadobutrol 1mmol/ml solution for injection 15ml vials · Gadobutrol 1mmol/ml solution for injection 30ml bottles · Gadobutrol 1mmol/ml solution for injection 7.5ml pre-filled syringes · Gadobutrol 1mmol/ml solution for injection 7.5ml vials · Gadovist · Gadovist 1mmol/ml solution for injection 10ml pre-filled syringes · Gadovist 1mmol/ml solution for injection 15ml vials · Gadovist 1mmol/ml solution for injection 30ml vials · Gadovist 1mmol/ml solution for injection 5ml pre-filled syringes · Gadovist 1mmol/ml solution for injection 65ml bottles · Gadovist 1mmol/ml solution for injection 7.5ml pre-filled syringes · Gadovist 1mmol/ml solution for injection 7.5ml vials

Denmark