Monograph
A02BB01 - Misoprostol |
Propably not porphyrinogenic |
PNP |
Rationale
Prostaglandin. Probably only insignificant hepatic exposure.
Chemical description
Tablets; 0.2-0.8 mg/d. Synthetic prostaglandin, which is inhibitor of ventricular secretion. Mucosaprotective effect against ASA induced ventricular lesions. Metabolized in several organs by beta-omega oxidation. Misoprostol and misoprostolic acid is excrered by the kidneys and faeces as various metabolites. South African list: use with extreme caution only. French list: authorized
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
Tradenames
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