B01AC06 - Acetylsalicylic Acid |
Propably not porphyrinogenic |
PNP |
Rationale
Inducer of 2C19. By vast experience known not to be porphyrinogenic. Several references: safe/authorised.
Chemical description
Water soluble platelet inhibitor, administered as tablets 75-500 mg/d. Hydrolyzed to salicylic acid. Excreted in urine. French list: Authorized. Kalman, Bonkowski: Believed to be safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89,1997: safe. Eales L: Porphyria and the lifethreatening drugs. S Afr Med J 56:914, 1974: safe. C.Andersson; patient reports: tolerated (n=2)
IPNet drug reports
Uneventful use reported in 92 patients with acute porphyria.
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