Monograph
C01CA04 - Dopamine |
Not porphyrinogenic |
NP |
Rationale
Endogenous substance. Non-CYP metabolism. No data pointing to CYP-interaction.
Therapeutic characteristics
Endogenous signal substance liberating noradrenaline. Used in shock due to its inotropic effect on heart minute volume.
Metabolism and pharmacokinetics
Metabolized by monoamine oxidase and COMT, primarily in the liver.
Personal communication
Stig Thunnel 2004: Used in Swedish porphyria ward.
References
| # | Citation details | PMID |
|---|---|---|
| * | Scientific articles | |
| 1. | Guideline for application of anesthesia in patients with porphyria. [German]. Anasthesiologie und Intensivmedizin 2002; 43(7-8):485-488.
Bohrer H, Olthoff D, Roewer N, Schulte am Esch HCJ. |
|
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Tradenames and packages
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